ADGRL1 / Unconjugated /

Product Details
Description ADGRL1 Antibody - middle region (OASG04206) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse, Rat
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications ELISA, IF
Supplier Aviva Systems Biology
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About ADGRL1
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
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