KCNMB3 / Unconjugated /

Product Details
Description Calcium activated K+ channels are comprised of two subunits: a large pore forming alpha subunit and a smaller modulatory beta subunit. Four splice variants of Kcnmb3 (beta 3) have been isolated that vary at the N-terminus and in their tissue distribution. Coexpression with BKalpha of all beta 3 splice variants resulted in only partial inactivation of the channel current.
Conjugate Unconjugated
Clone
Target Species Gorilla, Human
Applications IHC-P
Supplier Aviva Systems Biology
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About KCNMB3
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009]
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