RTN3 / Unconjugated / 1E11

Product Details
Description RTN3 Antibody (OAEC04529) Unconjugated Mouse Monoclonal Antibody, Reacts with Human
Conjugate Unconjugated
Clone 1E11
Target Species Human
Applications ELISA, IF
Supplier Aviva Systems Biology
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About RTN3
This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]
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