DPP10 / Unconjugated /
Product Details
| Description | DPP10 shares structural similarity with the dipeptidyl peptidase family, however it lacks the active site serine, which is substituted with a glycine residue. DPP10 has been shown to facilitate Kv4.2 protein trafficking to the cell membrane, increase A-type current magnitude and modify the voltage dependence and kinetic properties of the Kv4.2 channel. DPP10 is prominently expressed in all brain regions examined except cerebellum. | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | ||
| Target Species | Canine | |
| Applications | ELISA, IHC-P, WB | |
| Supplier | Aviva Systems Biology | |
| Catalog # | Sign in to view product details, citations, and spectra | |
| Size | ||
| Price | ||
| Antigen | ||
| Host | ||
| Isotype |
About DPP10
This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Experiment Design Tools
Panel Builders
Looking to design a Microscopy or Flow Cytometry experiment?
Validation References
| Additional Sources |
|
|---|
Reviews & Ratings
| Reviews |
|---|
Looking for more options?
189 DPP10 antibodies from over 15 suppliers available with over 41 conjugates.
Compare
