DCTN3 / Unconjugated /

Product Details
Description DCTN3 Antibody (OACA08755) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human
Conjugate Unconjugated
Clone
Target Species Human
Applications ELISA, IHC
Supplier Aviva Systems Biology
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About DCTN3
This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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