BIRC8 / Unconjugated /

Product Details

Description	Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2.
Conjugate	Unconjugated
Clone
Target Species	Human, Mouse, Rat
Applications	IHC-P, ICC, WB
Supplier	Aviva Systems Biology
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About BIRC8
Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; positive regulation of canonical Wnt signaling pathway; and positive regulation of protein ubiquitination. Predicted to be active in cytoplasm; nucleus; and spindle microtubule. [provided by Alliance of Genome Resources, Apr 2022]

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