APRT / Unconjugated /

Product Details
Description APRT Antibody (OAAN01294) Unconjugated Rabbit Polyclonal Antibody, Reacts with Human, Mouse, Rat
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications IF, WB, IHC
Supplier Aviva Systems Biology
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About APRT
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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