JNK1 / Unconjugated / 2F3
Product Details
| Description | JNK1, a MAPK type protein kinase, regulates cell apoptosis, differentiation and growth in response to growth factors, inflammatory cytokines and cellular stress. JNK1 is phosphorylated by MKK4/MAP2K4 and MKK7/MAP2K7. Activated JNK1 translocates to the nucleus where it phosphorylates transcription factors, including c-Jun, ATF2, ELK1, Jun-D and NFAT4. At least four alternatively spliced transcript variants encoding distinct isoforms, 384 and 427 amino acids, have been identified. | |
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| Conjugate | Unconjugated | |
| Clone | 2F3 | |
| Target Species | Human | |
| Applications | ELISA, IHC-P, WB, IP | |
| Supplier | Aviva Systems Biology | |
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