CC Chemokine Receptor D6 / Unconjugated /

Product Details
Description Chemokine Receptor D6 (CCBP2) antibody - N-terminal region
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications WB, IHC
Supplier Aviva Systems Biology
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About CC Chemokine Receptor D6
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008]
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