AOF1 / Unconjugated /
Product Details
| Description | Rabbit polyclonal to KDM1B.Lysine-specific histone demethylase 1B (KDM1B) belongs to the flavin monoamine oxidase family.KDM1B is a histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetictranscriptional activation, thereby acting as a corepressor. KDM1B is required for de novo DNAmethylation of a subset of imprinted genes during oogenesis. KDM1B demethylates both mono-anddi-methylated 'Lys-4' of histone H3, but has no effect on tri-methylated 'Lys-4' or other methylated Lysresidues of histone H3 or H4. | |
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| Conjugate | Unconjugated | |
| Clone | ||
| Target Species | Human | |
| Applications | WB, IP, ChIP | |
| Supplier | Biorbyt | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About AOF1
Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009]
Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009]
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119 AOF1 antibodies from over 14 suppliers available with over 34 conjugates.
