HIF-1 alpha / HiLyte 488 / H1alpha67
Product Details
| Conjugate | HiLyte 488 | |
|---|---|---|
| Clone | H1alpha67 | |
| Target Species | Avian, Bovine, Canine, Ferret, Human, Mouse, Porcine, Primate, Rabbit, Rat, Sheep | |
| Applications | KD, ELISA, FC, Knockout Validated, ICC, IF, Microscopy, IHC-P, WB, IP, IHC | |
| Supplier | Novus Biologicals | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About HIF-1 alpha
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
About HiLyte 488
HiLyte™ Fluor 488 from AnaSpec has an excitation peak at 497 nm and an emission peak at 525 nm.
HiLyte™ Fluor 488 from AnaSpec has an excitation peak at 497 nm and an emission peak at 525 nm.
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1454 HIF-1 alpha antibodies from over 29 suppliers available with over 67 conjugates.
