L-Caldesmon / Unconjugated / h-CALD

Product Details
Description Mouse monoclonal antibody to CALD1
Conjugate Unconjugated
Clone h-CALD
Target Species Human
Applications IHC-P
Supplier Biorbyt
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About L-Caldesmon
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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