ZAK / Unconjugated /

Product Details
Description Rabbit polyclonal antibody to ZAK
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications IF, ICC, WB
Supplier Biorbyt
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About ZAK
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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