SUMO2 / Unconjugated /

Product Details
Description Rabbit polyclonal to SUMO2.SMT3 suppressor of mif two 3 homolog 2 (SUMO2) is a member of the small ubiquitin-like modifierprotein family. It is a ubiquitin-like protein that can bind to a target protein as part of a posttranslationalmodification. However, instead of targeting proteins for degradation, it is involved in anumber of cellular processes, such as nuclear transport, DNA replication and repair, transcriptionalregulation, mitosis, apoptosis, and protein stability. In order for SUMO2 to be active, the last twoamino acids on the carboxy-terminus must be cleaved.
Conjugate Unconjugated
Clone
Target Species Human
Applications WB
Supplier Biorbyt
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About SUMO2
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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