SMAC / Unconjugated /
Product Details
Description | Rabbit Polyclonal SMAC/Diablo Antibody | |
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Conjugate | Unconjugated | |
Clone | ||
Target Species | Human | |
Applications | IF, IHC-P, WB | |
Supplier | OriGene | |
Catalog # | Sign in to view product details, citations, and spectra | |
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Antigen | ||
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About SMAC
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
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135 SMAC antibodies from over 16 suppliers available with over 34 conjugates.