SETD2 / Unconjugated / OTI1E1
Product Details
| Description | SETD2 mouse monoclonal antibody, clone OTI1E1 (formerly 1E1) | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | OTI1E1 | |
| Target Species | Human | |
| Applications | WB, IHC | |
| Supplier | OriGene | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About SETD2
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
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217 SETD2 antibodies from over 16 suppliers available with over 34 conjugates.
