RTKN / Unconjugated / OTI1A4
Product Details
| Description | Carrier-free (BSA/glycerol-free) RTKN mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | OTI1A4 | |
| Target Species | Human | |
| Applications | IF, WB, IHC | |
| Supplier | OriGene | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About RTKN
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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200 RTKN antibodies from over 14 suppliers available with over 35 conjugates.
