PCNA / Unconjugated / PC10

Product Details
Description Mouse Monoclonal Anti-PCNA Antibody, Purified
Conjugate Unconjugated
Clone PC10
Target Species Human, Insect, Mouse, Rat, Yeast
Applications IF, ICC, WB, IHC
Supplier OriGene
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About PCNA
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
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