PCNA / Unconjugated / OTI3F11
Product Details
| Description | PCNA mouse monoclonal antibody, clone OTI3F11 (formerly 3F11) | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | OTI3F11 | |
| Target Species | Human | |
| Applications | WB, IHC | |
| Supplier | OriGene | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About PCNA
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
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1419 PCNA antibodies from over 39 suppliers available with over 64 conjugates.
