NDUFB9 / Unconjugated / OTI4F8

Product Details
Description Carrier-free (BSA/glycerol-free) NDUFB9 mouse monoclonal antibody, clone OTI4F8 (formerly 4F8)
Conjugate Unconjugated
Clone OTI4F8
Target Species Canine, Human, Mouse, Rat
Applications WB, IHC
Supplier OriGene
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About NDUFB9
The protein encoded by this gene is a subunit of the mitochondrial oxidative phosphorylation complex I (nicotinamide adenine dinucleotide: ubiquinone oxidoreductase). Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q. Complex I deficiency is the most common defect found in oxidative phosphorylation disorders and results in a range of conditions, including lethal neonatal disease, hypertrophic cardiomyopathy, liver disease, and adult-onset neurodegenerative disorders. Pseudogenes of this gene are found on chromosomes five, seven and eight. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
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