MSH2 / Unconjugated / clone UMAB259
Product Details
| Description | MSH2 mouse monoclonal antibody,clone UMAB259 | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | clone UMAB259 | |
| Target Species | Human | |
| Applications | IHC | |
| Supplier | OriGene | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About MSH2
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
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