SMAD7 / Unconjugated /

Product Details
Description Rabbit polyclonal antibody to SMAD7
Conjugate Unconjugated
Clone
Target Species Mouse, Rat
Applications WB
Supplier Biorbyt
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About SMAD7
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
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378 SMAD7 antibodies from over 19 suppliers available with over 33 conjugates.

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