RSF1 / Unconjugated /

Product Details

Description	Rabbit polyclonal to RSF1.Remodeling and spacing factor 1 SF1) is a nuclear protein required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. RSF1 facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappa-B transcription activation. RSF1 represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain.
Conjugate	Unconjugated
Clone
Target Species	Human
Applications	WB
Supplier	Biorbyt
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About RSF1
This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone. [provided by RefSeq, Sep 2011]

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