PUMA / Unconjugated /

Product Details
Description Rabbit polyclonal to PUMA.
Conjugate Unconjugated
Clone
Target Species Human
Applications ELISA, IHC-P, WB
Supplier Biorbyt
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About PUMA
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
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535 PUMA antibodies from over 22 suppliers available with over 53 conjugates.

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