pIgR / Unconjugated /

Product Details
Description Rabbit polyclonal antibody to The human polymeric immunoglobulin receptor (PIGR), also called membrane secretory component (SC), is synthesized by secretory epithelial cells and delivered to the basolateral plasma membrane where it can bind larger polymers of IgA (pIgA ) and pentameric IgM.
Conjugate Unconjugated
Clone
Target Species Human
Applications ELISA, FC, IF, IHC-P, ICC, WB
Supplier Biorbyt
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About pIgR
This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009]
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