Piccolo / ATTO 680 / 6H9-B6

Product Details

Description	Mouse monoclonal to Piccolo (ATTO 680). Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1..
Conjugate	ATTO 680
Clone	6H9-B6
Target Species	Human, Rat
Applications	ELISA, WB
Supplier	Biorbyt
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About Piccolo
The protein encoded by this gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

About ATTO 680
ATTO 680 from ATTO-Tec Gmbh has an excitation peak at 680 nm and an emission peak at 700 nm.

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