PHYH / PE / S210-5

Product Details
Description Mouse monoclonal to PHYH (RPE). Phytanoyl-CoA alpha-hydroxylase (PHYH) is also called Phytanoyl-CoA dioxygenase, peroxisomal, Phytanic acid oxidase and the gene names PHYH or PAHX. PAHX is involved in lipid metabolism and converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. PAHX is expressed in liver, kidney, and T-cells. Defects in PHYH can cause Refsum disease (RD)..
Conjugate PE
Clone S210-5
Target Species Human, Rat
Applications IF, ICC, WB
Supplier Biorbyt
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About PHYH
This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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229 PHYH antibodies from over 15 suppliers available with over 51 conjugates.

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