PHYH / ATTO 390 / S210-5

Product Details
Description Mouse monoclonal to PHYH (ATTO 390). Phytanoyl-CoA alpha-hydroxylase (PHYH) is also called Phytanoyl-CoA dioxygenase, peroxisomal, Phytanic acid oxidase and the gene names PHYH or PAHX. PAHX is involved in lipid metabolism and converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. PAHX is expressed in liver, kidney, and T-cells. Defects in PHYH can cause Refsum disease (RD)..
Conjugate ATTO 390
Clone S210-5
Target Species Human, Rat
Applications IF, ICC, WB
Supplier Biorbyt
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About PHYH
This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
About ATTO 390
ATTO 390 from ATTO-Tec Gmbh has an excitation peak at 390 nm and an emission peak at 448 nm.
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