p53 / ATTO 680 / Pab 1801
Product Details
| Description | Mouse monoclonal antibody against p53 conjugated to ATTO 680. | |
|---|---|---|
| Conjugate | ATTO 680 | |
| Clone | Pab 1801 | |
| Target Species | Human | |
| Applications | ELISA, FC, IHC-P, WB, IP, IHC-Fr | |
| Supplier | Biorbyt | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About p53
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
About ATTO 680
ATTO 680 from ATTO-Tec Gmbh has an excitation peak at 680 nm and an emission peak at 700 nm.
ATTO 680 from ATTO-Tec Gmbh has an excitation peak at 680 nm and an emission peak at 700 nm.
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