Nitrotyrosine / ATTO 655 / 39B6
Product Details
Description | Mouse monoclonal to Nitrotyrosine (ATTO 655). Protein tyrosine nitration results in a post-translational modification that is increasingly receiving attention as an important component of nitric oxide signaling. While multiple nonenzymatic mechanisms are known to be capable of producing nitrated tyrosine residues, most tyrosine nitration events involve catalysis by metalloproteins such as myeloperoxidase, eosino-philperoxidase, myoglobin, the cytochrome P-450s, superoxide dismutase and prostacyclin synthase. Nitrotyrosine may also serve as a biomarker for the effects of reactive nitrogen oxides, based on tyrosine residues becoming nitrated in proteins at sites of inflammation induced tissue injury. The presence of nitro tyrosine-containing proteins therefore has shown high correlation to disease states such as atherosclerosis, Alzheimers disease, Parkinsons disease and amyotrophic lateral sclerosis.. | |
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Conjugate | ATTO 655 | |
Clone | 39B6 | |
Target Species | Canine, Human, Rat | |
Applications | ELISA, IF, IHC-P, ICC, WB, IP | |
Supplier | Biorbyt | |
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About ATTO 655
ATTO 655 from ATTO-Tec Gmbh has an excitation peak at 663 nm and an emission peak at 684 nm.
ATTO 655 from ATTO-Tec Gmbh has an excitation peak at 663 nm and an emission peak at 684 nm.
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166 Nitrotyrosine antibodies from over 16 suppliers available with over 54 conjugates.