FGF-R1 / Unconjugated / OTI3C4

Product Details
Description FGFR1 mouse monoclonal antibody, clone OTI3C4 (formerly 3C4)
Conjugate Unconjugated
Clone OTI3C4
Target Species Human
Applications WB
Supplier OriGene
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About FGF-R1
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Experiment Design Tools
Conjugation Options

Pair this antibody with compatibility secondary antibodies, and conjugation kits and services:

Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
Additional
Sources
Reviews & Ratings
Looking for more options?

808 FGF-R1 antibodies from over 22 suppliers available with over 40 conjugates.

Supplier Page
 Compare