Caspase 4 / Unconjugated /

Product Details
Description Rabbit polyclonal anti-Caspase-4 antibody, Aff - Purified
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications WB, IHC
Supplier OriGene
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About Caspase 4
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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