MMP27 / Unconjugated /

Product Details
Description Rabbit polyclonal to MMP27.Matrix metalloproteinase-27 (MMP27) belongs to the peptidase M10A family. Matrixmetalloproteinases (MMPs) degrade protein components of the extracellular matrix such asfibronectin, laminin, gelatins and/or collagens. MMPs are secreted by tumor cells themselves or bysurrounding stromal cells stimulated by the nearby tumor. Synthetic or natural inhibitors of MMPsresult in inhibition of metastasis, while up-regulation of MMPs leads to enhanced cancer cell invasion.
Conjugate Unconjugated
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Target Species Human, Mouse
Applications WB
Supplier Biorbyt
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About MMP27
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. [provided by RefSeq, Jul 2008]
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