CYP11B2 / Unconjugated /
Product Details
| Description | Rabbit polyclonal antibody to Cyp11B2 is a member of the cytochrome P450 superfamily of enzymes. It is involved in substrate recognition, conversion and catalyzes the conversion of 11- deoxycorticosterone to aldosterone. This is done by corticosterone and 18- hydroxycorticosterone. Genetic variation in CYP11B2. As a result, they are the cause of corticosterone methyloxidase type 1 deficiency. | |
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| Conjugate | Unconjugated | |
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| Target Species | Human, Mouse, Rat | |
| Applications | ELISA, IF, IHC-P, ICC | |
| Supplier | Biorbyt | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CYP11B2
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008]
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008]
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121 CYP11B2 antibodies from over 12 suppliers available with over 20 conjugates.
