CD161 / Unconjugated /
Product Details
| Description | Rabbit polyclonal antibody to CD161 which also known as NKR-P1 which expressed in a subset of NK cells predominantly in intestinal epithelium and liver. CD161 plays an inhibitory role on natural killer (NK) cells cytotoxicity. CD161 appears to mediate NK cell activation and is up-regulated by IL-12. | |
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| Conjugate | Unconjugated | |
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| Target Species | Human, Mouse, Rat | |
| Applications | ELISA, WB | |
| Supplier | Biorbyt | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD161
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
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1618 CD161 antibodies from over 42 suppliers available with over 130 conjugates.
