CARD8 / Unconjugated /

Product Details
Description Rabbit polyclonal antibody to CARD8
Conjugate Unconjugated
Clone
Target Species Human
Applications ELISA, IF, IHC-P, WB
Supplier Biorbyt
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About CARD8
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
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151 CARD8 antibodies from over 16 suppliers available with over 27 conjugates.

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