C4BPB / Unconjugated /

Product Details
Description Rabbit polyclonal antibody to C4BPB
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications IF, IHC-P, ICC, WB
Supplier Biorbyt
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About C4BPB
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
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201 C4BPB antibodies from over 12 suppliers available with over 18 conjugates.

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