BAZ2A / Unconjugated /

Product Details

Description	Rabbit polyclonal antibody to BAZ2A also known as TTFI5 or Tip5 whose expression can be detected in the heart and kidney but it is highly expressive in the placenta and pancreas. It is found in the nuclear speck. It is found in the microtubule cytoskeleton. BAZ2A plays an extensive role in RNA polymerase I CORE element sequence-specific DNA binding and chromatin remodeling. It binds with a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing.
Conjugate	Unconjugated
Clone
Target Species	Human, Mouse, Porcine, Rat
Applications	IF, IHC-P, ICC, WB
Supplier	Biorbyt
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About BAZ2A
Enables histone binding activity. Contributes to RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in DNA methylation; histone deacetylation; and negative regulation of macromolecule metabolic process. Predicted to act upstream of or within chromatin organization and histone modification. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

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