488

Laser Line

585/42

Common Filter

499

Excitation Max

594

Emission Max

About JC-1


JC-1 is a ratiometric probe used in cell health and apoptosis applications to detect changes to the polarity of the mitochondrial membrane. As the mitochondrial membrane potential neutralizes, this dye shifts to a monomeric form with an emission peak at 520 nm (green). When the mitochondrial potential is healthy, the probe aggregates in the membrane causing a shift it its emission to 590 nm (orange).



Spectra