JC-1 Dye Profile
488
Laser Line585/42
Common Filter499
Excitation Max594
Emission MaxAbout JC-1
JC-1 is a ratiometric probe used in cell health and apoptosis applications to detect changes to the polarity of the mitochondrial membrane. As the mitochondrial membrane potential neutralizes, this dye shifts to a monomeric form with an emission peak at 520 nm (green). When the mitochondrial potential is healthy, the probe aggregates in the membrane causing a shift it its emission to 590 nm (orange).
Spectra
Dyes similar to JC-1 based on emission
Check to add to spectra viewerATTO 565 ATTO Rho11 ATTO Rho12 ATTO Rho3B AccuOrange Alexa Fluor 568 Alizarin Red BOBO-3 BODIPY 581/591 Brilliant Violet 605 CF570 CF575 Calcein Red-Orange AM CellTracker Red Cy3.5 DY-510XL DY-511XL DsRed Express DsRed2 Dyomics 590 EMA GelRed KikGR1 (red) LipidSpot 488 Live-or-Dye 375/600 Live-or-Dye NucFix Red Live/Dead Fix Orange LysoBrite Red MitoLite Red FX600 MitoTracker Red NeuroVue Red NovaFluor Blue 585 NovaFluor Yellow 590 PE-Dyomics 590 PROTEOSTAT-Red PhenoVue Cal-590 AM Bright, Calcium Indicator PhenoVue Cal-590 AM, Calcium Indicator PhenoVue Fluor 400LS PhenoVue 512 Nucleic Acid Stain PhenoVue 577 Lysosomal Stain PhenoVue 578 Mitochondrial Stain PhenoVue Fluor 568 Qdot 585 RealYellow 586 Rhodamine Red-X Spark YG 593 SuperBright 600 Synapto Green TFAX 568 SE VivaFix 583/603 X-Rhod-1 (Ca2+ bound) eFluor 585NC mApple mRuby mScarlet mStrawberry pHrodo Red