cleaved Retinoblastoma 1

Aliases: OSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110
Other: retinoblastoma-associated protein|GOS563 exon 17 substitution mutation causes premature stop|exon 17 tumor GOS561 substitution mutation causes premature stop|prepro-retinoblastoma-associated protein|protein phosphatase 1, regulatory subunit 130|retinoblastoma 1|retinoblastoma suspectibility protein

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder... see more

DyLight 680

Common Laser: 628-640
Common Filter: 695/40
Excitation Peak: 692
Emission Peak: 712

DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.


Popular cleaved Retinoblastoma 1 DyLight 680 Antibodies


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 Browse cleaved Retinoblastoma 1 / DyLight 680 antibodies.