cleaved Retinoblastoma 1
| Aliases: | OSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110 |
|---|---|
| Other: | retinoblastoma-associated protein|GOS563 exon 17 substitution mutation causes premature stop|exon 17 tumor GOS561 substitution mutation causes premature stop|prepro-retinoblastoma-associated protein|protein phosphatase 1, regulatory subunit 130|retinoblastoma 1|retinoblastoma suspectibility protein |
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder... see more
DyLight 488
| Common Laser: | 488 |
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| Common Filter: | 525/50 |
| Excitation Peak: | 493 |
| Emission Peak: | 518 |
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
Popular cleaved Retinoblastoma 1 DyLight 488 Antibodies
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