Aliases: OSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110
Other: retinoblastoma-associated protein|GOS563 exon 17 substitution mutation causes premature stop|exon 17 tumor GOS561 substitution mutation causes premature stop|prepro-retinoblastoma-associated protein|protein phosphatase 1, regulatory subunit 130|retinoblastoma 1|retinoblastoma suspectibility protein

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder... see more

Alexa Fluor 488

Common Laser: 488
Common Filter: 530/43
Excitation Peak: 496
Emission Peak: 519

Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less suscept... see more


Popular cleaved Retinoblastoma 1 Alexa Fluor 488 Antibodies


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 Browse cleaved Retinoblastoma 1 / Alexa Fluor 488 antibodies.